The Centre County Kepone Site, located in Centre County, State College, Pennsylvania, includes the 32.3-acre chemical manufacturing facility of raw materials and solvents to produce soap, detergent, agricultural chemicals, pharmaceuticals, metal plating chemicals, and plastics. The facility also produced two pesticides, kepone and mirex, which were found in site soil, sediment, and biota over a three decades-long period. Once soil and groundwater were contaminated, affected groundwater originating at the Site flowed toward Thornton Spring and Spring Creek, presumably from the time the plant was constructed in 1957 to the end of production in 2003. Analysis of site-related data found that the aquatic invertebrate and fish communities were depressed in the 6.1-kilometer reach of Spring Creek downstream from Thornton Spring and was attributed to releases from the Centre County Kepone Site. Currently the Trustee Council is in settlement negotiations with the PRPs.